How Does Glycogen Catabolism Develop -

How Does Glycogen Catabolism Develop

glucose catabolism

This is what is referred to as the breakdown of glucose. There are a number of different processes through which this occurs. One such process involves the glycolysis process in which the liver breaks down glucose into glucose.

Another part of the process involves an increase in the activity of an enzyme. The enzyme, which is referred to as AMP (alpha monosalicylate), is important for glucose catabolism. When the AMP level increases, the activity of the glycolysis is increased. This increased activity promotes production of energy in the body, which helps to support metabolism and the burning of glucose.

Glucose Can Be Lost From The Body

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There are a number of ways in which glucose can be lost from the body. The first is where there is a substantial amount of glucose that is produced in the body and then used up before being put into use. The energy in this glucose is then used up by the production of insulin. The glucose that is produced in this way has to be taken into the blood, where it is used by the cells for their energy requirements. If insulin cannot enter a cell due to the lack of sufficient amounts of insulin, glucose is stored and this causes the production of glucose to increase again, leading to an increase in the amount of glucose in the blood. The more glucose that is produced, the higher the levels of glucose in the blood, causing a rise in blood glucose levels.

Production of glucose by the pancreas is then required to replenish the glucose so that it can go on to do its work. This is why hypoglycemia can occur, whereby there is an abnormally low level of insulin in the bloodstream. If the insulin level in the bloodstream is too low, the pancreas will not be able to store enough glucose to cover the energy requirements of the body and this will lead to the release of glucose to supply the energy requirements of the body. The pancreas responds by releasing more insulin, which in turn provides more glucose to the bloodstream.

Breaking Down Glycogen In The Muscles

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As mentioned above, one of the main ways in which glucose catabolism works is by breaking down glycogen in the muscles to convert it into glucose. If there are insufficient glycogen reserves in the muscle, then the body will require increasing the level of glucose being used to break down glycogen in order to provide it with energy.

The production of glycogen tends to be highest in the evenings, when the muscles are at their highest at rest. Glycogen is stored in the liver and it is believed that this is the reason why athletes feel so relaxed after training as they have high levels of glucose in their muscles, allowing the glycogen levels to rise.

Glucose Is Broken Down To Glucose

In addition to glucose catabolism, another important process for the body is glycolysis, which is the process in which glucose is broken down to glucose. The brain generates a chemical called GABA (gamma-aminobutyric acid) that allows it to relax and enable glucose to be released. This GABA emission is however inhibited when glucose is present in the bloodstream, which slows the process of glycolysis.

Glycogen is used in the liver for energy production, but when there is low availability in the bloodstream, the liver cannot produce enough GABA for it to relax and allow the brain to use glucose as an energy source. Glycogen is therefore stored in liver cells to be used when there is a deficit in the bloodstream and consequently, in the long run, glucose metabolism is slow to develop in spite of increased energy requirements.

Providing Energy To The Body

Catabolism plays an important role in providing energy to the body. When you perform physical exercise or undertake any form of energetic activity, your body uses up glucose and glycogen reserves. It is during the recovery phase of these activities that glycogen is converted into glucose, which is then stored for future energy requirements. It is during the later part of the day when carbohydrate consumption is reduced because of reduced calorie requirement and glycogen levels are slowly depleted. As a result of this low level of glycogen, the brain is unable to use glycogen to provide energy, leading to periods of weakness, dizziness, reduced alertness and drowsiness.

When you undertake aerobic exercises, you will burn up about twice as much energy as you would if you did the same amount of physical activity at a lower intensity. This means that you would need twice as much glycogen stores as you would if you carried out the same activity at a higher intensity, allowing for a slower development of glycogen metabolism.


In a study carried out by colleagues at University College London, it was found that elderly people who carried out moderate exercise on a regular basis were able to maintain their energy level (that is, their glucose levels did not fall below normal), even when their glycogen levels were severely depleted. The reason for this was that their bodies had formed a vast reserve of glucose in their muscles, liver and so forth, enabling them to fulfil their energy needs.

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